ABCB11 Polyclonal Antibody | G-AB-12217

ABCB11 Polyclonal Antibody | G-AB-12217 | Gentaur Antibodies

Overview: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Metabolism, Signal Transduction

Synonyms: ABCB11, ABC16, BRIC2, BSEP, PFIC-2, PFIC2, PGY4, SPGP

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 8647

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human ABCB11 (NP_003733.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: O95342

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ABCB11 Polyclonal Antibody DataSheet