ABCD2 Polyclonal Antibody | G-AB-09280

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$156.96 - $334.80
SKU:
G-AB-09280
Availability:
3 to 5 Working Days
Host:
Rabbit
Reactivity:
Human, Mouse, Rat
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ABCD2 Polyclonal Antibody | G-AB-09280 | Gentaur Antibodies

Overview: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters. Mutations in this gene have been observed in patients with adrenoleukodystrophy, a severe demyelinating disease. This gene has been identified as a candidate for a modifier gene, accounting for the extreme variation among adrenoleukodystrophy phenotypes. This gene is also a candidate for a complement group of Zellweger syndrome, a genetically heterogeneous disorder of peroxisomal biogenesis.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Metabolism, Signal Transduction

Synonyms: ABCD2, ABC39, ALDL1, ALDR, ALDRP, hALDR

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 225

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human ABCD2 (NP_005155.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9UBJ2

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ABCD2 Polyclonal Antibody DataSheet

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  • 4
    best price

    Posted by Chase on 17th Dec 2021

    The low price increase the customer demand and makes the company more stable! Gentaur is best for this

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