ABCG5 Polyclonal Antibody | G-AB-12285

ABCG5 Polyclonal Antibody | G-AB-12285 | Gentaur Antibodies

Overview: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Metabolism, Signal Transduction

Synonyms: ABCG5, STSL

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 64240

Accession #:

Clonality:

Immunogen: A synthetic peptide of human ABCG5 (NP_071881.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9H222

Santa Cruz:

Calculated MW: 28 kDa/72 kDa

Observed MW: 80 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ABCG5 Polyclonal Antibody DataSheet