ACOD1 Polyclonal Antibody | G-AB-04922

ACOD1 Polyclonal Antibody | G-AB-04922 | Gentaur Antibodies

Overview: Involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs) -mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells; ACOD1-mediated itaconic acid production contributes to the antimicrobial activity of macrophages. Plays a role in the embryo implantation.

Category Type: Polyclonal Antibody

Research Areas: Metabolism, Immunology, Signal Transduction

Synonyms: ACOD1, Aconitate decarboxylase 1, Aconitate decarboxylase, CAD, Cis aconitate decarboxylase, Immune responsive gene 1 protein homolog, Immune-responsive gene 1 protein homolog, Immunoresponsive 1 homolog (mouse) , Irg1, IRG1, OC116, OPTB1, TCTIRC7

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP001245335

Clonality: Polyclonal

Immunogen: Synthetic peptide of human ACOD1

Clone #:

Conjugation: Unconjugated

Swissprot: A6NK06

Santa Cruz:

Calculated MW: 53 kDa

Observed MW: Refer to figures

Concentration: 1.32 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: WB, ELISA

Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ACOD1 Polyclonal Antibody DataSheet