ACTL6B Polyclonal Antibody | G-AB-11508

ACTL6B Polyclonal Antibody | G-AB-11508 | Gentaur Antibodies

Overview: The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain. Alternative splicing results in multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Neuroscience, Stem cells

Synonyms: ACTL6B, ACTL6, BAF53B, arpNalpha

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 51412

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human ACTL6B (NP_057272.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: O94805

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC, IF

Dilution: IHC 1:50-1:200 IF 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ACTL6B Polyclonal Antibody DataSheet