ACTN2 Polyclonal Antibody | G-AB-10365

ACTN2 Polyclonal Antibody | G-AB-10365 | Gentaur Antibodies

Overview: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Signal Transduction

Synonyms: ACTN2, CMD1AA, CMH23

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 88

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human ACTN2 (NP_001094.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P35609

Santa Cruz:

Calculated MW: 103 kDa

Observed MW: 104 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IF

Dilution: WB 1:500-1:2000 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ACTN2 Polyclonal Antibody DataSheet