ADAM11 Polyclonal Antibody | G-AB-08628

ADAM11 Polyclonal Antibody | G-AB-08628 | Gentaur Antibodies

Overview: This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded preproprotein is proteolytically processed to generate the mature protease. This gene represents a candidate tumor suppressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Signal Transduction

Synonyms: ADAM11, MDC

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 4185

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human ADAM11 (NP_002381.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: O75078

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ADAM11 Polyclonal Antibody DataSheet