ADAMTS2 Polyclonal Antibody | G-AB-07353

ADAMTS2 Polyclonal Antibody | G-AB-07353 | Gentaur Antibodies

Overview: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature procollagen N-proteinase. This proteinase excises the N-propeptide of the fibrillar procollagens types I-III and type V. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Category Type: Polyclonal Antibody

Research Areas:

Synonyms: ADAMTS2, ADAM-TS2, ADAMTS-2, ADAMTS-3, NPI, PC I-NP, PCI-NP, PCINP, PCPNI, PNPI

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 216725

Accession #:

Clonality:

Immunogen: Recombinant protein of mouse ADAMTS2

Clone #:

Conjugation: Unconjugated

Swissprot: Q8C9W3

Santa Cruz:

Calculated MW: 61 kDa/134 kDa

Observed MW: 120 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ADAMTS2 Polyclonal Antibody DataSheet