AGR2 Polyclonal Antibody | G-AB-11477

AGR2 Polyclonal Antibody | G-AB-11477 | Gentaur Antibodies

Overview: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This protein plays a role in cell migration, cellular transformation and metastasis and is as a p53 inhibitor. As an ER-localized molecular chaperone, it plays a role in the folding, trafficking, and assembly of cysteine-rich transmembrane receptors and the cysteine-rich intestinal gylcoprotein mucin. This gene has been implicated in inflammatory bowel disease and cancer progression.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Developmental Biology, Stem Cells

Synonyms: AGR2, AG-2, AG2, GOB-4, HAG-2, HEL-S-116, HPC8, PDIA17, XAG-2

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 10551

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human AGR2 (NP_006399.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: O95994

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

AGR2 Polyclonal Antibody DataSheet