AIRE Polyclonal Antibody | G-AB-09713

AIRE Polyclonal Antibody | G-AB-09713 | Gentaur Antibodies

Overview: This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED) .

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Immunology

Synonyms: AIRE, AIRE1, APECED, APS1, APSI, PGA1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 326

Accession #:

Clonality:

Immunogen: A synthetic peptide of human AIRE (NP_000374.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: O43918

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

AIRE Polyclonal Antibody DataSheet