AKAP12 Polyclonal Antibody | G-AB-02950

AKAP12 Polyclonal Antibody | G-AB-02950 | Gentaur Antibodies

Overview: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in Signal Transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Neuroscience, Signal Transduction

Synonyms: A kinase (PRKA) anchor protein (gravin) 12, A kinase Anchor Protein 12, A kinase anchor protein 250kDa, A-kinase anchor protein 12, A-kinase anchor protein 250 kDa, AKA12, AKAP 12, AKAP 250, AKAP-12, Akap12, AKAP250, DKFZp686M0430, DKFZp686O0331, FLJ20945, FLJ97621, Gercelin, Gravin, Kinase scaffold protein gravin, Myasthenia gravis autoantigen, Myasthenia gravis autoantigen gravin, OTTHUMP00000017426, OTTHUMP00000017427, Src-Suppressed C Kinase Substrate, Srcs5, SSeCKS, Tsga12

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_005091

Clonality: Polyclonal

Immunogen: Synthetic peptide of human AKAP12

Clone #:

Conjugation: Unconjugated

Swissprot: Q02952

Santa Cruz: sc-9805/sc-9806/sc-48117/sc-48119/sc-48116/sc-48118/sc-33577

Calculated MW: 191 kDa

Observed MW:

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:200-1:1000, IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

AKAP12 Polyclonal Antibody DataSheet