ALKBH2 Polyclonal Antibody | G-AB-00686

ALKBH2 Polyclonal Antibody | G-AB-00686 | Gentaur Antibodies

Overview: The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine. Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1-ethenoadenine (in vitro) . Has strong preference for double-stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron.

Category Type: Polyclonal Antibody

Research Areas: Epigenetics and Nuclear Signaling

Synonyms: 2OG Fe (II) oxy DC1, 9530023G02, ABH 2, ABH2, alkB alkylation repair homolog 2, ALKB2, ALKBH2 alkB, ALKBH2, Alkylated DNA repair protein alkB homolog, Alkylated DNA repair protein alkB homolog 2, Alkylation repair homolog 2, Alpha ketoglutarate dependent dioxygenase alkB homolog 2, Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2, AU016977, DNA oxidative demethylase ALKBH2, EC 1.14.11., FLJ99103, hABH2, mABH2, MGC90512, Oxy DC1

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC070489

Clonality: Polyclonal

Immunogen: Recombinant protein of human ALKBH2

Clone #:

Conjugation: Unconjugated

Swissprot: Q6NS38

Santa Cruz: sc-161335

Calculated MW: 29 kDa

Observed MW:

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, ELISA

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ALKBH2 Polyclonal Antibody DataSheet