ALOXE3 Polyclonal Antibody | G-AB-12107

ALOXE3 Polyclonal Antibody | G-AB-12107 | Gentaur Antibodies

Overview: This gene is a member of the lipoxygenase family, which are catabolized by arachidonic acid-derived compounds. The encoded enzyme is a hydroperoxide isomerase that synthesizes a unique type of epoxy alcohol (8R-hydroxy-11R, 12R-epoxyeicosa-5Z, 9E, 14Z-trienoic acid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE) . This epoxy alcohol can activate the the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha) , which is implicated in epidermal differentiation. Loss of function of the enzyme encoded by this gene results in ichthyosis, implicating the function of this gene in the differentiation of human skin. This gene is part of a cluster of lipoxygenase genes on 17p13.1. Mutations in this gene result in nonbullous congenital ichthyosiform erythroderma (NCIE) . Multiple transcript variants encoding different isoforms have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Metabolism, Signal Transduction

Synonyms: ALOXE3, ARCI3, E-LOX, eLOX-3, eLOX3

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 59344

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human ALOXE3 (NP_067641.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9BYJ1

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ALOXE3 Polyclonal Antibody DataSheet