ALPL Polyclonal Antibody | G-AB-07444

ALPL Polyclonal Antibody | G-AB-07444 | Gentaur Antibodies

Overview: This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific) . The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Tags & Cell Markers

Synonyms: ALPL, AP-TNAP, APTNAP, HOPS, TNAP

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 249

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human ALPL (NP_000469.3) .

Clone #:

Conjugation: Unconjugated

Swissprot: P05186

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ALPL Polyclonal Antibody DataSheet