AMACR Polyclonal Antibody | G-AB-12700
- 3 to 5 Working Days
- Mouse, Rat
AMACR Polyclonal Antibody | G-AB-12700 | Gentaur Antibodies
Overview: AMACR (Alpha-methylacyl-CoA racemase) belongs to the CaiB/BaiF CoA-transferase family. It is a mitochondrial and peroxisomal enzyme that catalyzes the conversion of 2R stereoisomers of phytanic and pristanic acid to their S counterparts. AMACR has previously been shown to be a highly sensitive marker for colorectal and clinically localized prostate cancer (PCa) . However, AMACR expression is down-regulated at the transcript and protein level in hormone-refractory metastatic PCa, suggesting a hormone-dependent expression of AMACR. It has 3 isoforms produced by alternative splicing. Defects in AMACR are the cause of alpha-methylacyl-CoA racemase deficiency (AMACRD) and congenital bile acid synthesis defect type 4 (CBAS4) .
Category Type: Polyclonal Antibody
Research Areas: Cell Biology, Metabolism, Signal Transduction
Synonyms: 2 methylacyl CoA racemase, 2-methylacyl-CoA racemase, Alpha methylacyl CoA racemase, Alpha-methylacyl-CoA racemase, Amacr, AMACR, AMACRD, Macr1, RACE, RM
Reactivity: Mouse, Rat
Gene ID: 17117
Immunogen: Recombinant Mouse Alpha-methylacyl-CoA racemase protein
Calculated MW: 42 kDa
Observed MW: 40 kDa
Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
Purification method: Antigen Affinity Purification
Application: WB, IHC
Dilution: WB 1:1000-1:3000 IHC 1:100-1:200
Storage: Store at -20℃. Avoid freeze / thaw cycles.