Amphiphysin II Polyclonal Antibody | G-AB-01950

Amphiphysin II Polyclonal Antibody | G-AB-01950 | Gentaur Antibodies

Overview: This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Microbiology

Synonyms: AMPH 2, AMPH2, Amphiphysin 2, Amphiphysin II, Amphiphysin like protein, amphiphysin-like, Amphiphysin-like protein, AMPHL, Bin1, BIN1, Box Dependant MYC Interacting Protein 1, Box-dependent myc-interacting protein 1, Bridging integrator 1, DKFZp547F068, MGC10367, MGC105358, Myc box dependent interacting protein 1, Myc box-dependent-interacting protein 1, SH3P9

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC004101

Clonality: Polyclonal

Immunogen: Recombinant protein of human BIN1

Clone #:

Conjugation: Unconjugated

Swissprot: O00499

Santa Cruz: sc-8534/sc-30099

Calculated MW:

Observed MW:

Concentration: 0.1 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Amphiphysin II Polyclonal Antibody DataSheet