AMPKα2 Polyclonal Antibody | G-AB-11639
Gentaur Antibodies
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Gentaur Antibodies
AMPKα2 Polyclonal Antibody | G-AB-11639
- SKU:
- G-AB-11639
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
AMPKα2 Polyclonal Antibody | G-AB-11639 | Gentaur Antibodies
Overview: The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK) . AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR) , key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cardiovascular, Metabolism, Signal Transduction
Synonyms: PRKAA2, AMPK, AMPK2, AMPKa2, PRKAA
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID: 5563
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human AMPKα2 (NP_006243.2) .
Clone #:
Conjugation: Unconjugated
Swissprot: P54646
Santa Cruz:
Calculated MW: 62 kDa
Observed MW: 69 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB, IF
Dilution: WB 1:500-1:2000 IF 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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