ANAPC5 Polyclonal Antibody | G-AB-11509

ANAPC5 Polyclonal Antibody | G-AB-11509 | Gentaur Antibodies

Overview: This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C) , a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b) , compared to isoform a.

Category Type: Polyclonal Antibody

Research Areas: Cell Biology

Synonyms: ANAPC5, APC5

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 51433

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human ANAPC5 (NP_057321.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9UJX4

Santa Cruz:

Calculated MW: 25 kDa/72 kDa/85 kDa

Observed MW: 85 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC

Dilution: WB 1:500-1:2000 IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ANAPC5 Polyclonal Antibody DataSheet