ANGPT1 Polyclonal Antibody | G-AB-11918

ANGPT1 Polyclonal Antibody | G-AB-11918 | Gentaur Antibodies

Overview: This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Metabolism

Synonyms: ANGPT1, AGP1, AGPT, ANG1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 284

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human ANGPT1 (NP_001186788.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q15389

Santa Cruz:

Calculated MW: 57 kDa

Observed MW: 51 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC

Dilution: WB 1:500-1:2000 IHC 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ANGPT1 Polyclonal Antibody DataSheet