ANGPT1 Polyclonal Antibody | G-AB-11918
- 3 to 5 Working Days
- Human, Mouse, Rat
ANGPT1 Polyclonal Antibody | G-AB-11918 | Gentaur Antibodies
Overview: This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cardiovascular, Metabolism
Synonyms: ANGPT1, AGP1, AGPT, ANG1
Reactivity: Human, Mouse, Rat
Gene ID: 284
Immunogen: Recombinant fusion protein of human ANGPT1 (NP_001186788.1) .
Calculated MW: 57 kDa
Observed MW: 51 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB, IHC
Dilution: WB 1:500-1:2000 IHC 1:50-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.