ANO1 Polyclonal Antibody | G-AB-07402

ANO1 Polyclonal Antibody | G-AB-07402 | Gentaur Antibodies

Overview: TMEM16A, also known as DOG1, ORAOV2, TAOS2 or ANO1 (anoctamin 1) , is a 986 amino acid multi-pass membrane protein that localizes to both the cell membrane and the cytoplasm and belongs to the anoctamin family. Expressed in a variety of tissues with highest expression in skeletal muscle and liver, TMEM16A functions as a calcium-activated chloride channel that is required for normal tracheal development. Human TMEM16A shares 90% sequence identity with its mouse counterpart, suggesting a conserved role between species. TMEM16A is present in breast, pancreatic, gastric, and uterine cancers, as well as in neck, ovarian and parathyroid tumors, suggesting a role for TMEM16A in carcinogenesis. Three isoforms of TMEM16A exist due to alternative splicing events.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Tags & Cell Markers

Synonyms: ANO1, DOG1, ORAOV2, TAOS2, TMEM16A

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 55107

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human ANO1 (NP_060513.5) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q5XXA6

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:100-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ANO1 Polyclonal Antibody DataSheet