ANTXR1 Polyclonal Antibody | G-AB-11149

ANTXR1 Polyclonal Antibody | G-AB-11149 | Gentaur Antibodies

Overview: This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Microbiology, Tags & Cell Markers

Synonyms: ANTXR1, ATR, GAPO, TEM8

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 84168

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human ANTXR1 (NP_060623.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9H6X2

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ANTXR1 Polyclonal Antibody DataSheet