ANTXR1 Polyclonal Antibody | G-AB-11149
- 3 to 5 Working Days
- Human, Mouse
ANTXR1 Polyclonal Antibody | G-AB-11149 | Gentaur Antibodies
Overview: This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cardiovascular, Microbiology, Tags & Cell Markers
Synonyms: ANTXR1, ATR, GAPO, TEM8
Reactivity: Human, Mouse
Gene ID: 84168
Immunogen: Recombinant fusion protein of human ANTXR1 (NP_060623.2) .
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Dilution: IF 1:50-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.