ANXA7 Polyclonal Antibody | G-AB-01896

ANXA7 Polyclonal Antibody | G-AB-01896 | Gentaur Antibodies

Overview: Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins.The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the use of two alternative poly (A) signals. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties, including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Signal Transduction

Synonyms: Annexin A7, Annexin VII, Annexin-7, ANX7, ANXA7, ANXA7, SNX, Synexin

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC002632

Clonality: Polyclonal

Immunogen: Recombinant protein of human ANXA7

Clone #:

Conjugation: Unconjugated

Swissprot: P20073

Santa Cruz: sc-1932/sc-55488/sc-11389

Calculated MW:

Observed MW:

Concentration: 0.8 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:150-1:300

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ANXA7 Polyclonal Antibody DataSheet