APAF1 Polyclonal Antibody | G-AB-01199
Gentaur Antibodies
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Gentaur Antibodies
APAF1 Polyclonal Antibody | G-AB-01199
- SKU:
- G-AB-01199
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
APAF1 Polyclonal Antibody | G-AB-01199 | Gentaur Antibodies
Overview: This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD) , and an ATPase domain (NB-ARC) . Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cell Biology, Metabolism
Synonyms: APAF 1, Apaf-1, APAF, Apaf1, Apoptotic peptidase activating factor 1, Apoptotic protease activating factor 1, Apoptotic protease activating factor, Apoptotic protease-activating factor 1, CED 4, CED4, KIAA0413
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #: NP_863659
Clonality: Polyclonal
Immunogen: Synthetic peptide of human APAF1
Clone #:
Conjugation: Unconjugated
Swissprot: O14727
Santa Cruz: sc-7231/sc-26685/sc-7232/sc-33870/sc-33871/sc-65890/sc-65891/sc-65890/sc-65891/sc-8339
Calculated MW: 142 kDa
Observed MW:
Concentration: 0.7 mg/mL
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Application: WB, IHC, ELISA
Dilution: WB 1:500-1:2000, IHC 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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