APAF1 Polyclonal Antibody | G-AB-07229
Gentaur Antibodies
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Gentaur Antibodies
APAF1 Polyclonal Antibody | G-AB-07229
- SKU:
- G-AB-07229
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human
APAF1 Polyclonal Antibody | G-AB-07229 | Gentaur Antibodies
Overview: This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD) , and an ATPase domain (NB-ARC) . Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cell Biology, Metabolism
Synonyms: APAF1, APAF-1, CED4
Reactivity: Human
Host: Rabbit
Isotype: IgG
Gene ID: 317
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human APAF1 (NP_863651.1) .
Clone #:
Conjugation: Unconjugated
Swissprot: O14727
Santa Cruz:
Calculated MW: 37 kDa/133 kDa/135 kDa/137 kDa/140 kDa/141 kDa
Observed MW: 142 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB
Dilution: WB 1:500-1:2000
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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