ARC Polyclonal Antibody | G-AB-02218

ARC Polyclonal Antibody | G-AB-02218 | Gentaur Antibodies

Overview: Arc (for activity-regulated cytoskeleton-associated protein) is a growth factor and immediate early gene that is enriched in brain. Arc mRNA and protein levels are induced by neuronal activity, which is necessary to stimulate neuroplasticity, indicating a potential role for Arc in activity-dependent changes in dendrite function. Arc expression has been detected in neuronal cell bodies and dendrites in the hippocampus, amygdala, hypothalamus, striatum and cortex. Arc has been shown to localize to the cytoskeleton of neuronal cells and appears to colocalize with F-Actin, although it may associate with an Actin-associated protein rather than directly with F-Actin. It has been shown that cocaine-stimulated neuronal activity results in increased Arc mRNA levels in striatum.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Neuroscience

Synonyms: activity regulated cytoskeleton associated protein, activity regulated gene 3.1 protein homolog, Activity-regulated cytoskeleton-associated protein, Activity-regulated gene 3.1 protein homolog, Arc, ARC/ARG3.1, ARC, Arg3.1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC012321

Clonality: Polyclonal

Immunogen: Recombinant protein of human ARC

Clone #:

Conjugation: Unconjugated

Swissprot: Q7LC44

Santa Cruz: sc-33947/sc-6381/sc-6382/sc-15325

Calculated MW: 45 kDa

Observed MW:

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ARC Polyclonal Antibody DataSheet