ARID1A Polyclonal Antibody | G-AB-01550

ARID1A Polyclonal Antibody | G-AB-01550 | Gentaur Antibodies

Overview: This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction

Synonyms: actin-dependent regulator of chromatin subfamily F member 1, ARI1A, ARID domain containing protein 1A, ARID domain-containing protein 1A, ARID1A, AT rich interactive domain 1A (SWI like) , AT rich interactive domain 1A, AT rich interactive domain containing protein 1A, AT-rich interactive domain-containing protein 1A, B120, BAF250, BAF250A, BM029, brain protein 120, BRG1 associated factor 250, BRG1 associated factor 250a, BRG1-associated factor 250, BRG1-associated factor 250a, C1ORF4, chromatin remodeling factor p250, chromosome 1 open reading frame 4, ELD, hELD, hOSA1, matrix-associated, MRD14, Osa homolog 1, OSA1, OSA1 nuclear protein, P270, SMARCF1, SWI like protein, SWI SNF complex protein p270, SWI-like protein, SWI/SNF complex protein p270, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily f, member 1, SWI/SNF-related

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_006006

Clonality: Polyclonal

Immunogen: Synthetic peptide of human ARID1A

Clone #:

Conjugation: Unconjugated

Swissprot: O14497

Santa Cruz: sc-103404/sc-98441/sc-48791

Calculated MW:

Observed MW:

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ARID1A Polyclonal Antibody DataSheet