ASIP Polyclonal Antibody | G-AB-11347

ASIP Polyclonal Antibody | G-AB-11347 | Gentaur Antibodies

Overview: In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adult-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may (1) affect the quality of hair pigmentation, (2) act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone, (3) play a role in neuroendocrine aspects of melanocortin action, and (4) have a functional role in regulating lipid metabolism in adipocytes.

Category Type: Polyclonal Antibody

Research Areas:

Synonyms: ASIP, AGSW, AGTI, AGTIL, ASP, SHEP9

Reactivity: Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 434

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human ASIP (NP_001663.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P42127

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ASIP Polyclonal Antibody DataSheet