ATF4 Polyclonal Antibody | G-AB-11575

ATF4 Polyclonal Antibody | G-AB-11575 | Gentaur Antibodies

Overview: This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2) . The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: ATF4, CREB-2, CREB2, TAXREB67, TXREB

Reactivity: Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 468

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human ATF4 (NP_001666.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P18848

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ATF4 Polyclonal Antibody DataSheet