ATG4D Polyclonal Antibody | G-AB-11896
- 3 to 5 Working Days
- Human, Mouse, Rat
ATG4D Polyclonal Antibody | G-AB-11896 | Gentaur Antibodies
Overview: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene belongs to the autophagy-related protein 4 (Atg4) family of C54 endopeptidases. Members of this family encode proteins that play a role in the biogenesis of autophagosomes, which sequester the cytosol and organelles for degradation by lysosomes. Alternative splicing results in multiple transcript variants.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cell Biology, Cardiovascular, Metabolism, Signal Transduction
Synonyms: ATG4D, APG4-D, APG4D, AUTL4
Reactivity: Human, Mouse, Rat
Gene ID: 84971
Immunogen: Recombinant fusion protein of human ATG4D (NP_116274.3) .
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Dilution: IF 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.