ATP6V1A Polyclonal Antibody | G-AB-08778

ATP6V1A Polyclonal Antibody | G-AB-08778 | Gentaur Antibodies

Overview: This gene encodes a component of vacuolar ATPase (V-ATPase) , a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain A subunit isoforms and is found in all tissues. Transcript variants derived from alternative polyadenylation exist.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Metabolism, Signal Transduction, Tags & Cell Markers

Synonyms: ATP6V1A, ATP6A1, ATP6V1A1, HO68, VA68, VPP2, Vma1, ARCL2D

Reactivity: Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 523

Accession #:

Clonality:

Immunogen: A synthetic peptide of human ATP6V1A (NP_001681.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P38606

Santa Cruz:

Calculated MW: 64 kDa/68 kDa

Observed MW: 74 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ATP6V1A Polyclonal Antibody DataSheet