ATR Polyclonal Antibody | G-AB-06968

ATR Polyclonal Antibody | G-AB-06968 | Gentaur Antibodies

Overview: The protein encoded by this gene belongs the PI3/PI4-kinase family, and is most closely related to ATM, a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with Schizosaccharomyces pombe rad3, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This kinase has been shown to phosphorylate checkpoint kinase CHK1, checkpoint proteins RAD17, and RAD9, as well as tumor suppressor protein BRCA1. Mutations of this gene are associated with Seckel syndrome. An alternatively spliced transcript variant of this gene has been reported, however, its full length nature is not known. Transcript variants utilizing alternative polyA sites exist.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: Ataxia telangiectasia and Rad3 related, Ataxia telangiectasia and Rad3-related protein, ATR, ATR, FCTCS, FRAP Related Protein 1, FRAP-related protein 1, FRP1, MEC1, MEC1 mitosis entry checkpoint 1 homolog, Protein kinase ATR, RAC3, Rad3 related protein, SCKL, SCKL1, Serine/threonine protein kinase ATR, Serine/threonine-protein kinase ATR

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP001175

Clonality: Polyclonal

Immunogen: Synthetic peptide of human ATR

Clone #:

Conjugation: Unconjugated

Swissprot: Q13535

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1.1 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: IHC, ELISA

Dilution: IHC 1:40-1:200, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ATR Polyclonal Antibody DataSheet