ATRX Polyclonal Antibody | G-AB-04818

ATRX Polyclonal Antibody | G-AB-04818 | Gentaur Antibodies

Overview: The protein encoded by this gene contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Mutations in this gene are associated with an X-linked mental retardation (XLMR) syndrome most often accompanied by alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.

Category Type: Polyclonal Antibody

Research Areas:

Synonyms: Alpha thalassemia/mental retardation syndrome X linked homolog, ATP dependent helicase ATRX, ATP-dependent helicase ATRX, ATR2, Atrx, ATRX, DNA dependent ATPase and helicase, Helicase 2, X linked, MGC2094, MRXHF1, RAD54, RAD54L, SFM1, SHS, Transcriptional regulator ATRX, X linked helicase II, X linked nuclear protein, X-linked helicase II, X-linked nuclear protein, XH2, XNP, Znf HX, Znf-HX

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP000480

Clonality: Polyclonal

Immunogen: Synthetic peptide of human ATRX

Clone #:

Conjugation: Unconjugated

Swissprot: P46100

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 0.7 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: IHC, ELISA

Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ATRX Polyclonal Antibody DataSheet