ATXN1 Polyclonal Antibody | G-AB-00839

ATXN1 Polyclonal Antibody | G-AB-00839 | Gentaur Antibodies

Overview: The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7) , and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5) , are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions.

Category Type: Polyclonal Antibody

Research Areas: Epigenetics and Nuclear Signaling, Neuroscience

Synonyms: alternative ataxin1, Ataxin-1, ATX1, ATX1, Atxn1, D6S504E, OTTHUMP00000016065, SCA1, Spinocerebellar ataxia type 1 protein

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC117125

Clonality: Polyclonal

Immunogen: Recombinant protein of human ATXN1

Clone #:

Conjugation: Unconjugated

Swissprot: P54253

Santa Cruz: sc-8766/sc-12526/sc-12527

Calculated MW:

Observed MW:

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ATXN1 Polyclonal Antibody DataSheet