BAG2 Polyclonal Antibody | G-AB-11856

BAG2 Polyclonal Antibody | G-AB-11856 | Gentaur Antibodies

Overview: BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

Category Type: Polyclonal Antibody

Research Areas: Cell Biology, Signal Transduction, Cancer, Metabolism

Synonyms: BAG2, BAG-2, dJ417I1.2

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 9532

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human BAG2 (NP_004273.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: O95816

Santa Cruz:

Calculated MW: 20 kDa/23 kDa

Observed MW: 24 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC, IF

Dilution: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

BAG2 Polyclonal Antibody DataSheet