BAX Monoclonal Antibody | G-AB-05686
- 3 to 5 Working Days
- Human, Mouse, Rat
BAX Monoclonal Antibody | G-AB-05686 | Gentaur Antibodies
Overview: Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Category Type: Monoclonal Antibody
Research Areas: Cancer, Cell Biology, Metabolism
Synonyms: Apoptosis regulator BAX, BAX, Bax-protein, BAX, BAXA, Baxdelta2G9, Baxdelta2G9omega, Baxdelta2omega, Bcl-2-like protein 4, BCL2 associated X protein, BCL2 associated X protein omega, BCL2 associated X protein transcript variant delta2, Bcl2-L-4, BCL2L4, membrane isoform alpha
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic Peptide of Bax
Clone #: Clone:1C1
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification method: Protein A purification
Dilution: IHC 1:100-200
Storage: Store at -20°C. Avoid freeze / thaw cycles.