BBC3 Polyclonal Antibody | G-AB-02714

BBC3 Polyclonal Antibody | G-AB-02714 | Gentaur Antibodies

Overview: This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Metabolism, Signal Transduction

Synonyms: BBC 3, Bbc3, BBC3, BCL 2 binding component 3, Bcl-2-binding component 3, BCL2 binding component 3, JFY 1, JFY-1, JFY1, p53 up regulated modulator of apoptosis, p53 up-regulated modulator of apoptosis, p53 Upregulated Modulator of Apoptosis, PUMA alpha, PUMA/JFY1

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_055232

Clonality: Polyclonal

Immunogen: Synthetic peptide of human BBC3

Clone #:

Conjugation: Unconjugated

Swissprot: Q9BXH1

Santa Cruz: sc-19191/sc-19187/sc-20534/sc-19190/sc-20536/sc-19188/sc-19189/sc-28226

Calculated MW: 21 kDa

Observed MW:

Concentration: 0.9 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, ELISA

Dilution: WB 1:200-1:1000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

BBC3 Polyclonal Antibody DataSheet