BBS4 Polyclonal Antibody | G-AB-10375

BBS4 Polyclonal Antibody | G-AB-10375 | Gentaur Antibodies

Overview: This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse. The similar phenotypes exhibited by mutations in BBS gene family members are likely due to the protein's shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene has sequence similarity to O-linked N-acetylglucosamine (O-GlcNAc) transferases in plants and archaebacteria and in human forms a multi-protein 'BBSome' complex with seven other BBS proteins. Alternate splicing results in multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas:

Synonyms: BBS4

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 585

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human BBS4 (NP_149017.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q96RK4

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

BBS4 Polyclonal Antibody DataSheet