Bim Polyclonal Antibody | G-AB-07849

Bim Polyclonal Antibody | G-AB-07849 | Gentaur Antibodies

Overview: The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3) . It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF) , as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Metabolism, Immunology, Neuroscience, Signal Transduction

Synonyms: BAM, BIM, BOD, Bim, BCL2L11

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 10018

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human Bim (NP_619527.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: O43521

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC, IF

Dilution: IHC 1:50-1:100 IF 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Bim Polyclonal Antibody DataSheet