BMI1 Polyclonal Antibody | G-AB-07129

BMI1 Polyclonal Antibody | G-AB-07129 | Gentaur Antibodies

Overview: This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1) . This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Stem Cells

Synonyms: BMI1, FLVI2/BMI1, PCGF4, RNF51, flvi-2/bmi-1, Bmi1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 648

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human BMI1 (NP_005171.4) .

Clone #:

Conjugation: Unconjugated

Swissprot: P35226

Santa Cruz:

Calculated MW: 36 kDa

Observed MW: 42 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

BMI1 Polyclonal Antibody DataSheet