BMPR2 Polyclonal Antibody | G-AB-09544

BMPR2 Polyclonal Antibody | G-AB-09544 | Gentaur Antibodies

Overview: This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Signal Transduction, Stem Cells

Synonyms: BMPR2, BMPR-II, BMPR3, BMR2, BRK-3, POVD1, PPH1, T-ALK

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 659

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human BMPR2 (NP_001195.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q13873

Santa Cruz:

Calculated MW: 59 kDa/115 kDa

Observed MW: 100 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC

Dilution: WB 1:500-1:2000 IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

BMPR2 Polyclonal Antibody DataSheet