BRAF Polyclonal Antibody | G-AB-08898

BRAF Polyclonal Antibody | G-AB-08898 | Gentaur Antibodies

Overview: This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Signal Transduction

Synonyms: BRAF, B-RAF1, B-raf, BRAF1, NS7, RAFB1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 673

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human BRAF (NP_004324.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P15056

Santa Cruz:

Calculated MW: 84 kDa

Observed MW: 105 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IF

Dilution: WB 1:500-1:2000 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

BRAF Polyclonal Antibody DataSheet