C10orf2 Polyclonal Antibody | G-AB-08235

C10orf2 Polyclonal Antibody | G-AB-08235 | Gentaur Antibodies

Overview: This gene encodes a hexameric DNA helicase which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. The protein localizes to the mitochondrial matrix and mitochondrial nucleoids. Mutations in this gene cause infantile onset spinocerebellar ataxia (IOSCA) and progressive external ophthalmoplegia (PEO) and are also associated with several mitochondrial depletion syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Category Type: Polyclonal Antibody

Research Areas:

Synonyms: TWNK, ATXN8, C10orf2, IOSCA, MTDPS7, PEO, PEO1, PEOA3, PRLTS5, SANDO, SCA8, TWINL

Reactivity: Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 56652

Accession #:

Clonality:

Immunogen: A synthetic peptide of human C10orf2 (NP_068602.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q96RR1

Santa Cruz:

Calculated MW: 60 kDa/66 kDa/77 kDa

Observed MW: 77 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

C10orf2 Polyclonal Antibody DataSheet