C4BPB Polyclonal Antibody | G-AB-06297

C4BPB Polyclonal Antibody | G-AB-06297 | Gentaur Antibodies

Overview: This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Immunology

Synonyms: C4b binding protein beta chain, C4b-binding protein beta chain, C4BP, C4BPB, C4BPB, Complement component 4 binding protein beta, Complement component 4 binding protein beta chain, Complement component 4-binding protein beta, OTTHUMP00000034288, OTTHUMP00000034289, OTTHUMP00000034375, OTTHUMP0000003474, Proline rich protein, PRP

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC005378

Clonality: Polyclonal

Immunogen: Fusion protein of human C4BPB

Clone #:

Conjugation: Unconjugated

Swissprot: P20851

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 0.7 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: IHC, ELISA

Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

C4BPB Polyclonal Antibody DataSheet