C9orf116 Polyclonal Antibody | G-AB-04194

C9orf116 Polyclonal Antibody | G-AB-04194 | Gentaur Antibodies

Overview: C9orf116, also known as PIERCE1. PIERCE1 is an important p53 target gene contributing to normal DNA damage response and may play crucial roles in maintaining genomic integrity against genotoxic stresses, including UVC irradiation. PIERCE1 exists as two alternatively spliced isoforms and is predominantly expressed in human small cell lung cancer. PIERCE1 knockdown induces down-regulation of proapoptotic genes including Ei24, Apaf1 and PTEN, suggesting that PIERCE1 is a proapoptotic gene. It is helpful for in-depth understanding of p53 pathways and the design of new cancer therapies.

Category Type: Polyclonal Antibody

Research Areas: Cell Biology

Synonyms: C9orf116, CI116, Pierce 1, UPF0691 protein C9orf116

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC021261

Clonality: Polyclonal

Immunogen: Fusion protein of human C9orf116

Clone #:

Conjugation: Unconjugated

Swissprot: Q5BN46

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 0.96 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

C9orf116 Polyclonal Antibody DataSheet