CACNA2D2 Polyclonal Antibody | G-AB-03587
Gentaur Antibodies
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Gentaur Antibodies
CACNA2D2 Polyclonal Antibody | G-AB-03587
- SKU:
- G-AB-03587
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
CACNA2D2 Polyclonal Antibody | G-AB-03587 | Gentaur Antibodies
Overview: Calcium channels mediate the entry of calcium ions into the cell upon membrane polarization. This gene encodes the alpha-2/delta subunit of the voltage-dependent calcium channel complex. The complex consists of the main channel-forming subunit alpha-1, and auxiliary subunits alpha-2/delta, beta, and gamma. The auxiliary subunits function in the assembly and membrane localization of the complex, and modulate calcium currents and channel activation/inactivation kinetics. The subunit encoded by this gene undergoes post-translational cleavage to yield the extracellular alpha2 peptide and a membrane-anchored delta polypeptide. This subunit is a receptor for the antiepileptic drug, gabapentin. Mutations in this gene are associated with early infantile epileptic encephalopathy. Single nucleotide polymorphisms in this gene are correlated with increased sensitivity to opioid drugs. Alternative splicing results in multiple transcript variants encoding different isoforms.
Category Type: Polyclonal Antibody
Research Areas: Cell Biology, Neuroscience, Signal Transduction
Synonyms: Alpha 2 delta calcium channel subunit, CA2D2, CACNA2D, Cacna2d2, Calcium channel, voltage-dependent, alpha 2/delta subunit 2, Calcium channel, voltage-dependent, alpha 2/delta subunit 2 gene 26, Calcium voltage gated channel auxiliary subunit alpha2delta 2, Gene 26, KIAA0558, LUAC11.1, Voltage-dependent calcium channel subunit alpha-2/delta-2, Voltage-dependent calcium channel subunit delta-2, Voltage-gated calcium channel subunit alpha-2/delta-2
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID:
Accession #: NP001167522
Clonality: Polyclonal
Immunogen: Synthetic peptide of human CACNA2D2
Clone #:
Conjugation: Unconjugated
Swissprot: Q9NY47
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 0.7 mg/mL
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification method: Antigen affinity purification
Application: IHC, ELISA
Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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