CAD Polyclonal Antibody | G-AB-12147
- 3 to 5 Working Days
- Human, Mouse, Rat
CAD Polyclonal Antibody | G-AB-12147 | Gentaur Antibodies
Overview: The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II) , aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism
Synonyms: CAD, CDG1Z, EIEE50, GATD4
Reactivity: Human, Mouse, Rat
Gene ID: 790
Immunogen: Recombinant fusion protein of human CAD (NP_004332.2) .
Calculated MW: 242 kDa
Observed MW: 243 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB, IHC, IF
Dilution: WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.