CAPN6 Polyclonal Antibody | G-AB-03898

CAPN6 Polyclonal Antibody | G-AB-03898 | Gentaur Antibodies

Overview: Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Signal Transduction

Synonyms: CALP M, Calpain-6, Calpain-like protease X-linked, Calpamodulin, CalpM, CAN6, CANP X, CANPX, CAPN 6, Capn6

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC000730

Clonality: Polyclonal

Immunogen: Fusion protein of human CAPN6

Clone #:

Conjugation: Unconjugated

Swissprot: Q9Y6Q1

Santa Cruz:

Calculated MW: 75 kDa

Observed MW: Refer to figures

Concentration: 0.78 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: WB, ELISA

Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CAPN6 Polyclonal Antibody DataSheet