CARD11 Polyclonal Antibody | G-AB-11526

CARD11 Polyclonal Antibody | G-AB-11526 | Gentaur Antibodies

Overview: The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD) . This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Immunology, Signal Transduction

Synonyms: CARD11, BENTA, BIMP3, CARMA1, IMD11, PPBL

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 84433

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human CARD11 (NP_115791.3) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9BXL7

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC, IF

Dilution: IHC 1:50-1:200 IF 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CARD11 Polyclonal Antibody DataSheet