CASP9 Monoclonal Antibody | G-AB-05542

CASP9 Monoclonal Antibody | G-AB-05542 | Gentaur Antibodies

Overview: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly (ADP-ribose) polymerase (PARP) .Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.

Category Type: Monoclonal Antibody

Research Areas: Cancer, Cell Biology, Metabolism

Synonyms: APAF-3, APAF3, Apoptosis related cysteine peptidase, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, CASP-9, CASP9, CASP9, Caspase 9 apoptosis related cysteine peptidase, Caspase 9 Dominant Negative, Caspase 9c, Caspase-9, Caspase-9 subunit p10, ICE LAP6, ICE like apoptotic protease 6, ICE-LAP6, ICE-like apoptotic protease 6, MCH6, PPP1R56, protein phosphatase 1, regulatory subunit 56, RNCASP9

Reactivity: Human

Host: Mouse

Isotype: IgG

Gene ID:

Accession #:

Clonality: Monoclonal

Immunogen: Synthetic Peptide

Clone #: Clone:3I3

Conjugation: Unconjugated

Swissprot: P55211

Santa Cruz:

Calculated MW: 46 kDa

Observed MW: 47-51 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Purification method: Protein A purification

Application: WB, IHC-p, IF, IP

Dilution: WB 1:500-1:2000, IHC 1:50-300, IF 1:50-1:200, IP 1:100-1:300

Storage: Store at -20°C. Avoid freeze / thaw cycles.

CASP9 Monoclonal Antibody DataSheet